Hemoglobin is an oxygen binding protein in erythrocytes. Hemoglobin is composed of four polypeptide chains. During the fetal stage the type of hemoglobin called fetal hemoglobin (HbF) dominates. After birth HbF is replaced by adult hemoglobin (HbA). HbF persists in concentrations less than 1%.

The danger and vulnerability associated with a preterm birth seem to be closely correlated with a dysfunction of the fetal hypothalamic-pituitary-adrenal (HPA) axis, whose maturation in the foal is without a doubt as delicate as it is important. Not only is this endocrine cascade vital for the foal in order to cope with neonatal stress, it also appears to be fundamental for the final fetal intrauterine maturation, as well as for the onset of foaling. Equine gestation exhibits some rather unique features, indicating a somewhat different significance of the endocrine changes associated with HPA maturation, compared to many other species. This hormonal cascade is rapid and confined to a narrow time during late gestation in the horse, and the risk of the foal completely missing it therefore becomes prominent. Induced parturition in the mare may be operated through uterotonic agents, which occasionally bring about premature foals. Desirable seems the ability to initiate equine labour while simultaneously enhancing fetal HPA maturation, as in humans and ruminants through perinatal glucocorticoid administration. However, similar treatment in the horse has resulted in various, sometimes fatal, outcomes. In the light of the distinctive features of equine gestation, difficulties are encountered following such administration of glucocorticoids and ACTH.

Hemoglobin is an oxygen binding protein in erythrocytes. Hemoglobin is composed of four polypeptide chains. During the fetal stage the type of hemoglobin called fetal hemoglobin (HbF) dominates. After birth HbF is replaced by adult hemoglobin (HbA). HbF persists in concentrations less than 1%.

In couples diagnosed with unexplained infertility, the woman has normal ovulatory cycles and no organic pathology, and the man has normal semen. The period during which the implantation of an embryo can occur is defined as the window of implantation (WOI). For infertile women, disturbances in the endometrium maturation are hypothesized to impair the uterine receptivity for embryo implantaition. However, there are still no methods found to predict endometrial receptivity.Hemoglobin related-proteins hypothesized to be involved in embryo implantation have been found in the endometrium in both fertile and infertile women. The aim of this study was to determine whether there were differences in the expression of hemoglobin-related proteins, hemoglobin-?, cytoglobin, fetal hemoglobin and haptoglobin in the endometrium of fertile and infertile women.

Renal dysplasi (RD) is a congenital chronic renal disease affecting young dogs. It is a rather common disease that occurs in a large number of dogs and in some breeds there is a familiar incidence or suspected hereditary background. Both the etiology and pathogenesis are still unknown, but a theory about the cause of RD is that the two components that form the kidney, the uretheric bud and the metanephrogenic blastema, don´t interact normally in the embryo. Kidneys affected by RD contain fetal (immature) structures that are inappropriate for the state of development/age of the dog and abnormal structures caused by an abnormal differentiation. Affected dogs usually are under .

Dystocia, or difficult birth, is a commonly seen complication to natural birth in veterinary hospitals. Although other methods of resolving dystocia exist, 60 % of dystocias will need to undergo caesarean section. To perform a caesarean section, the bitch will have to undergo anesthesia. The purpose of this literary study was to provide a deeper understanding regarding how the physiologic changes that occur during pregnancy influence anesthetic management in the bitch and puppies. Which anesthetic drugs and drug combinations indicated was also investigated as well as how a veterinary nurse can optimize care of the mother throughout the procedure and how resuscitation of the puppies should be carried out for best possible outcome.

Introduktion: Fosterdiagnostik med magnetkamerateknik (MR-teknik) har utvecklats mycket den senaste tiden och använts som en kompletterande metod till ultraljudsundersökning. Magnetkamera ger ingen joniserande strålning till patienterna, samt ger en mycket mer detaljerad bildinformation än vad andra metoder gör. I samband med MR kan de gravida kvinnorna uppleva olika psykiska påfrestningar genom både själva MR-undersökningen och oro för barnets hälsa. Även om MR-fosterdiagnostiken anses vara en säker undersökningsmetod för fostret föreligger det ändå en ovisshet angående de effekter som kan förekomma. Syfte: Syftet med examensarbetet är att genom publicerad forskning få kunskap som kan utveckla röntgensjuksköterskans möjlighet att ge optimalt stöd och information till gravida kvinnor vid fosterdiagnostik med MR-teknik utifrån följande aspekter: 1.

Enligt Statistiska Centralbyrån [SCB] föddes det år 2008 109 301 barn i Sverige. Utöver dessa föddes det cirka 600 barn som dött i livmodern innan förlossning. Intrauterin fosterdöd innebär att barn föds döda efter graviditetsvecka 22. Tidigare forskning belyser vikten av att barnmorskor har ett individuellt synsätt vid mötet med par vid intrauterin fosterdöd. Forskningen åskådliggör även hur föräldrar upplevt det stöd som givits under förlossningen.

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.

Background: The incidence of caesarean section for breech presentation has reached approximately 90 % in Sweden. In many of these cases, by means of specific selection criteria, it would be as safe to plan for vaginal breech delivery. Aim: The objective of this study was to investigate differences in management and to compare maternal and fetal outcomes according to delivery mode of breech presentation; vaginal vs. caesarian section. The study included breech presentation in full term singleton pregnancies at the UppsalaUniversityHospital, Uppsala, Sweden (UAS). Method: The study was based on medical record data with a retrospective, descriptive, comparative design with quantitative approach. The method for data collection was a manual review of patient records using a structured questionnaire. Results: Of the women with children in breech presentation during the period studied, 11 % gave birth vaginally.

Every spring you can see newborn foals running on fields among the mare. But some unfortunate end up visiting the equine hospital requiring surgery. This is a challenge for the anesthetist because of the neonatal foal?s unique physiology. Therefore you need to take these differences under consideration when you anesthetize foals.

Title: Are we born gifted or can we learn and teach our children to be musically interested? The aim of this study is to evaluate how we influence the development of musicality in children. The study included 30 persons divided into three groups (ten members in each group). Group 1 consisted of pregnant women. Group 2 consisted of parents of babies age 0 to 1 year old and group 3 teenage parents.

ABSTRACTThe aim of this study was to give an overview of the evidence for genomic imprinting in livestock and other mammals as well as outline the potential use of gene imprinting in livestock breeding. Epigenetics is the mitotical and meiotical partial hereditary variation in genomic activity without any alterations of the DNA sequence. An example of epigenetic regulation is genomic imprinting where one allele?s expression differs depending on which parent it was inherited from. These parent-of-origin effects are currently overlooked in livestock production.

Bakgrund: Den snabba tekniska utvecklingen har medfört förbättrade möjligheter till detaljerad och högkvalitativ fosterdiagnostik. Avvikelser i fostrets utveckling kan därför upptäckas på ett tidigt stadium i graviditeten. Att få ett besked om att fostret bär på en anomali är ofta entraumatisk upplevelse som försätter de blivande föräldrarna i svåra etiska dilemman. Fosterdiagnostik med MR är en relativt nyutvecklad modalitet som ger detaljerade och högkvalitativa bilder. Den forskning som genomförts hittills har främst handlat om magnetfältets inverkan på fostret medan det saknas kunskap om den gravida kvinnans upplevelse avundersökningen.

Bull terrier hereditary nephritis is caused by a mutation that leads to an inadequate synthesis of collagen type IV, which is an important component in the basement membranes. The inheritance of the mutation is autosomal dominant in bull terriers and progression to renal failure takes variable time, from several months to ten years. Proteinuria is the first clinical sign of the disease and the diagnosis is confirmed by transmission electron microscopy of renal tissue where typical ultrastructural changes in the glomerular basement membrane (GBM), thickening and multilaminar splitting are found. This study was performed in order to find out the occurrence of hereditary nephritis in bull terriers in Sweden through examination of urine samples and renal tissue and comparisons with how the disease is described in the literature. Urine samples from 76 Swedish bull terriers were collected and examined for proteinuria.